Abstracts accepted for ITMIG2025

(AB: 1). Sternal Elevation Subxiphoid Thoracoscopic Minimally Invasive Surgery for Giant Mediastinal Teratoma in Young Adults; Ye Yuan, POSTER PRESENTATION 

(AB: 2). Robot-Assisted Thoracic Surgery for Thymic Epithelial Tumors: A Real-World Study of 143 Cases; Benedikt Niedermaier, Nabil Khan, Florian Eichhorn, Heidrun Grosch, Michael Thomas, Hauke Winter, Martin Eichhorn POSTER PRESENTATION

(AB: 3). Histopathological heterogeneity in resected thymomas; Florit Marcuse, Myrurgia Abdul Hamid, Stephanie Peeters, Monique Hochstenbag, Jamie Romeo, Jos Maessen, Pilar Martinez, Marc De Baets, Axel Zur Hausen, POSTER PRESENTATION

 (AB: 4). Optimizing postoperative proton radiotherapy in thymic epithelial tumors: added value of breath hold?; Esther Kneepkens, Marije Velders, Judith van der Stoep, Maud Cobben, Maud van den Bosch, Nicole Hendrix, Ilaria Rinaldi, Dirk De Ruysscher, Dianne Hartgerink, Judith Van Loon, Stephanie Peeters, Florit Marcuse, POSTER PRESENTATION

(AB: 5). Optimizing Surgical Strategies in Mediastinal Tumor Resections through Comparative Analysis of Hemi-Clamshell and Sternotomy Techniques; Chengyuan Fang, Jingle Lei, Xiaodong Ling, Yingnan Yang, Huiying Li, Jianqun Ma, POSTER PRESENTATION

(AB: 6). Metaplastic Thymoma of the Mediastinum - A Clinicopathological Report of Three Cases;  Po-Kuei Hsu, Yi-Chen Yeh, Min-Shu Hsieh, POSTER PRESENTATION

(AB: 7). Postoperative Complications and Early Recurrence in Surgically Treated Thymoma: A Single-Centre Retrospective Study;  Abdurrahmaan Manga, Sameera Gamlath, Syed Mohammad, Elizabeth Stannard, Cathy Richards, Elizabeth Webb, Veeresh Patil, Jonathan Bennett, Rajini Sudhir, Sanjay Agrawal, Apostolos Nakas, Muhammad Majid, POSTER PRESENTATION

(AB: 8). Thymectomy in Patients with Thymoma-Associated Myasthenia Gravis; Chen Yuan, Wang Hao, Shi Yang, POSTER PRESENTATION with brief discussion

(AB: 10). Analysis of natural development and changes of thymic cysts on imaging; Wang Rong, POSTER PRESENTATION

(AB: 11). Review of case characteristics and exploration of mechanisms of thymoma shrinkage after glucocorticoid therapy; Shi Yang, Zhang Peng, Chen Yuan, POSTER PRESENTATION

(AB: 13). A Phase 1 Trial of PRTH-101, a monoclonal antibody targeting discoidin domain receptor 1 (DDR1), alone or in combination with pembrolizumab, for the treatment of thymic malignancies; Funda Meric-Bernstam, So Kim, Siraj Sen, Christopher Nabel, David Sommerhalder, Rachel Sanborn, Aparna Parikh, Julia Moore, Jordan Berlin, Patricia LoRusso, Guy Clifton, Thomas Shuerpf, Joseph Eder, Alex Spira, POSTER PRESENTATION with brief discussion

(AB: 14). Robot-Assisted Subxiphoid Approach for Resection of a Giant Cervicothoracic Junction Tumor: A Case Report; Yuwen Bai, Yanzhong Xin, Luquan Zhang, Xionghai Qin, Jianqun Ma, POSTER PRESENTATION

(AB: 15). Short-term outcome of robotic subxiphoid-optical thymectomy for malignant thymic epithelial tumors; Masayoshi Inoue, Masanori Shimomura, Satoru Okada, Tatsuo Furuya, Chiaki Nakazono, POSTER PRESENTATION

(AB: 16). A Pivotal Phase 2 Trial to Compare PRTH-101, a monoclonal antibody targeting discoidin domain receptor 1 (DDR1), in combination with an immune checkpoint inhibitor (ICI) and ICI alone, for the treatment of recurrent or metastatic thymic epithelial carcinoma (TEC); Joseph Eder, Irena Webster, POSTER PRESENTATION

(AB: 17). Autoreactome Analysis Reveals Novel Autoantibodies in Thymoma-Associated Myasthenia Gravis; Linda Kusner, Taylor Bauman, Henry Kaminski, Jiaxin Chen, ORAL PRESENTATION

(AB: 18). Perioperative Outcomes and Surgical Strategies in Malignant Anterior Mediastinal Tumors; Hao Jiang, Hao Liang, Jingfeng Zhang, Guanying Liang, Jianqun Ma, POSTER PRESENTATION 

(AB: 19). Towards Understanding Mechanisms of Thymectomy Benefit for Myasthenia Gravis; Henry Kaminski, Ali Taheriyoun, Keith Crandall, Ali Rahnavard, Linda Kusner, ORAL PRESENTATION

(AB: 20). Prognostic Nutritional Index and Neutrophil-to-Lymphocyte Ratio Composite Score Predicts Survival in Surgically Resected Thymic Epithelial Tumors: A Retrospective Single Centre Cohort Study;  Junnan Hu, Ke Ma, Xiang Zhuang, Yongtao Han, ​Hao Rong​​, ​Jun Peng, ​​Xin Gao, ​Nian Xu, ​​Qingjie Chen, ORAL PRESENTATION

(AB: 21). Clinicopathologic Features, Treatment Outcomes, and Survival in Thymic Neuroendocrine Tumors: A 25-Year Single-Center Experience; Aleksandra Piórek, Adam Płużański, Dariusz Kowalski, Maciej Krzakowski, POSTER PRESENTATION

(AB: 22). Targeted biologics for treating thymoma associated myasthenia gravis: a multicenter retrospective study; Lei Jin, Dingxian He, Hongxi Chen, Hongyu Zhou, Quantao Zeng, Song Tan, Jianquan Shi, Ying Liu, Zhangyu Zou, Jie Song, Chong Yan, Xiao Huan, Yuan Wang, Lei Yang, Jianying Xi, Zongtai Wu, Jianming Zheng, Chongbo Zhao, Xianglin Chu, Sushan Luo, POSTER PRESENTATION

(AB: 23). Single-cell analysis of tumor microenvironment and molecular features of thymic epithelial tumor subtypes; Myungsun Park, Gamin Kim, Wonrak Son, Yongjun Koh, Soyean Choi, Dawoon Na, Jeong Seok Lee, Chang Gon Kim, Yoon-La Choi, Hye Ryun Kim, Seong Yong Park, POSTER PRESENTATION

(AB: 24). Machine Learning Models from FDG PET/CT for Predicting Recurrence in Thymomas;  Angelo Castello, Luigi Manco, Margherita Cattaneo, Riccardo Orlandi, Lorenzo Rosso, Giorgio Croci, Luigia Florimonte, Giovanni Scribano, Stefano Ferrero, Mario Nosotti, Massimo Castellani, Gianpaolo Carrafiello, Paolo Mendogni, ORAL PRESENTATION

(AB: 25). Salvage surgery following definitive chemoradiotherapy and immune checkpoint inhibitor therapy for locally advanced thymic carcinoma: A case report; Ryosuke Tokuda, Satoshi Ikebe, Taishi Harada, Nishimura Saki, Masayoshi Inoue, POSTER PRESENTATION

(AB: 26). A single-arm, multicenter, phase II trial of glucocorticoids induction followed by surgery for advanced thymomas with type B component; NING XU, POSTER PRESENTATION

(AB: 29). Clinicopathological and histological features of the thymic hyperplasia combined with Sjögren’s syndrome: an open-label, single-arm observational study;  Kai Xiong, Peng Zhang, Peng Zhang, Yuan Chen, Yuanguo Wang, ORAL PRESENTATION

(AB: 33). Retrospective evaluation of cardiac toxicity during irradiation of thymic malignancies;  Camille Fradin, Nicolas Giraud, Jennifer Tatje, Maxime Angougeard, Claudia Pouypoudat, POSTER PRESENTATION with brief discussion

(AB: 35). Thymic epithelial tumors and immune system: a particular relationship still to be clarified; Emanuele Voulaz, Simone Balin, Emanuela Re Cecconi, Laura Russo, Matteo Perrino, Nadia Cordua, Silvia Della Bella, Giorgio Da Rin, Domenico Mavilio, Giuseppe Marulli, Paolo Zucali, POSTER PRESENTATION

(AB: 36). MIST: A Weakly Supervised Deep Learning System for Multicenter Diagnosis of Mediastinal Tumors;  Xiaofeng Jiang, Hengrui Liang, Jianxing He, Yongtao Han, Jakob Kather, Xuefeng Leng, ORAL PRESENTATION

(AB: 37). Case Report. When the Thymus Crosses the Line: An Unusual Case of Lung-Infiltrating Endobronchial Thymoma.; Giacomo Rabazzi, Vittorio Aprile, Maria Giovanna Mastromarino, Alessandra Lenzini, Stylianos Korasidis, Greta Alì, Iacopo Petrini, Marcello Carlo Ambrogi, Marco Lucchi, POSTER PRESENTATION

(AB: 38). Contralateral Pleura-Sparing Modified Subxiphoid Approach for Robotic Thymectomy: Operative Results, and Advantages in Metachronous Lung Cancer Resection; Takao Nakanishi, Ren Takehara, Taishi Adachi, Hideki Motoyama, Mitsugu Omasa, POSTER PRESENTATION

(AB: 39). Surgery for De Novo Stage IVa Thymomas: Time to Broaden Our Horizons? A single-centre retrospective analysis.; Giacomo Rabazzi, Vittorio Aprile, Stylianos Korasidis, Maria Giovanna Mastromarino, Alessandra Lenzini, Greta Alì, Iacopo Petrini, Marcello Carlo Ambrogi, Marco Lucchi, POSTER PRESENTATION

(AB: 40). Good’s Syndrome and infections in a large retrospective cohort of thymoma; Wenji Jia, POSTER PRESENTATION with brief discussion

(AB: 41). Eculizumab as a new option for perioperative treatment in thymoma-associated myasthenia gravis: a prospective case series; Hui Wu, Xianglin Chu, Huahua Zhong, Liewen Pang, Lei Jin, Wenji Jia, Ran Chen, Zongtai Wu, Ji Xiong, Chongbo Zhao, Jie Song, Sushan Luo, POSTER PRESENTATION

(AB: 42). Epstein-Barr Virus Expression in Thymoma and Its Clinical Relevance: A Single-Center Bidirectional Cohort Observational Study;  Hui Zhang, Peng Zhang, Yuan Chen, Xin Li, Yimei Liu, Yuanguo Wang, Pengjie Tu, Runze Li, Jinwei Zhang, Jian Li, POSTER PRESENTATION

(AB: 43). Clinical significance of SUVmax as a predictor of pathological invasion and prognostic factor in advanced thymic epithelial tumors requiring a combined resection of adjacent organs and dissemination; Satoru Okada, POSTER PRESENTATION with brief discussion

(AB: 44). Eculizumab as a new option for perioperative treatment in thymoma-associated myasthenia gravis: a prospective case series; Hui Wu, Sushan Luo,

(AB: 45). Global patterns and trends in thymic epithelial tumors incidence: worldwide healthcare disparity on detection; Bincheng Jiang, Zhitao Gu, Teng Mao, Wentao Fang, ORAL PRESENTATION

(AB: 46). Central pathology review of thymic tumors: updated analysis of diagnostic concordance in the French RYTHMIC cohort;  Álvaro Gutiérrez, Lara Chalabreysse, Jean-Philippe Dales, Romain Dubois, Véronique Hofman, Audrey Mansuet-Lupo, Anne de Muret, Nicolas Piton, Isabelle Rouquette, Véronique Secq, Damien Sizaret, Vincent Thomas de Montpréville, José Carlos Benítez, Angela Botticella, Daniela Miliziano, Lodovica Zullo, Pascale Missy, Jordi Remón, Nicolas Girard, Benjamin Besse, Thierry Molina, ORAL PRESENTATION

(AB: 47). Thymic Cancer in France: A Comprehensive Analysis of Incidence Based on French National Healthcare Data;  Álvaro Gutiérrez, Alexandre Lolivier, Jose Carlos Benitez, Jordi Remón, Adrien Rousseau, David Planchard, Fabrice Barlesi, Pernelle Lavaud, Anas Gazzah, Claudia Parisi, Pamela Abdayem, Daniela Miliziano, Lodovica Zullo, Martina Gasparro, Diego Diaz-Jimenez, Nicolas Girard, Vincent Thomas de Montpreville, Olaf Mercier, Stephanie Foulon, Benjamin Besse, ORAL PRESENTATION

(AB: 48). Weakly Supervised AI-Based Subtyping of Thymic Epithelial Tumors Using H&E Whole Slide Images; Anna Salut Esteve Domínguez, Farhan Akram, Stephanie Peeters, Lara Chalabreysse, Nicolas Girard, Dirk De Ruysscher, Jan von der Thusen, ORAL PRESENTATION

(AB: 49). PD-1 checkpoint inhibitors exhibit significant antitumor activity in patients with Masaoka stage IV thymoma; Hua Liu, POSTER PRESENTATION

(AB: 50). Trends in thymic epithelial tumor patients in the Netherlands, a population-based study; Marlou Dimmers, Florit Marcuse, Lex Maat, Jos Maessen, Jamie Romeo, Monique Hochstenbag, Stephanie Peeters, Ties Mulders, Jan von der Thüsen, Sabrina Siregar, Daphne Dumoulin, POSTER PRESENTATION

(AB: 51). The safety of surgery plus hyperthermic intrathoracic chemotherapy perfusion in patients with IVa TETs;   Xuefei Zhang, Ning Xu, Teng Mao, POSTER PRESENTATION

(AB: 53). A 10-Year Retrospective Review of Recurrent Thymomas: A Single-Centre Experience; Anchal Jain, Maria Leite, Rhona Taberham, Dionisios Stavroulias, POSTER PRESENTATION

(AB: 54). Survival of Danish patients with thymic epithelial tumours; Tine Østergaard, Caroline V. A. Bjerke, Eric Santoni-Rugiu, Thomas Jensen, Katharina Perell, René Petersen, Peter Petersen, POSTER PRESENTATION

(AB: 56). Subclinical myasthenia gravis after thymectomy: A 20-Year retrospective cohort study; Florit Marcuse, Janneke Hoeijmakers, Myrurgia Abdul Hamid, Jamie Romeo, Jos Maessen, Stephanie Peeters, Jan Damoiseaux, Pilar Martinez, Monique Hochstenbag, Marc De Baets, POSTER PRESENTATION

(AB: 57). INDUCTION THERAPY FOLLOWED BY SURGERY IN UNRESECTABLE THYMIC EPITHELIAL TUMORS OVER THE PAST 20 YEARS: EVIDENCE FROM A SYSTEMATIC REVIEW AND META-ANALYSIS;  Michele Ferrari, Giovanni Leuzzi, Federica Sabia, Ugo Pastorino, Alessandro Pardolesi, Alessia Stanzi, Claudia Proto, Giuseppe Lo Russo, Arsela Prelaj, Monica Ganzinelli, Matteo Calderoni, Clarissa Uslenghi, Piergiorgio Solli, POSTER PRESENTATION

(AB: 58). TREATMENT RESPONSE AFTER INDUCTION THERAPY IN UNRESECTABLE THYMIC TUMORS: TYME DATABASE ANALYSIS;  Giovanni Leuzzi, Federica Sabia, Claudia Proto, Giuseppe Lo Russo, Monica Ganzinelli, Alessandra Fabbri, Matteo Perrino, Nadia Cordua, Alessandro Bertocchi, Antonio Federico, Paolo Zucali, Marco Lucchi, Marcello Ambrogi, Vittorio Aprile, Paolo Mendogni, Fabiana Cecere, Giovanni Comacchio, Marianna Tortora, Marzia Di Pietro Paolo, Piergiorgio Solli, POSTER PRESENTATION with brief discussion

(AB: 59). Myasthenia Gravis Following Thymectomy: Insights from a Multicenter Retrospective Cohort Study;  Francesco Guerrera, Filippo Lococo, Eleonora Faccioli, Vittorio Aprile, Pietro Bertoglio, Paraskevas Lyberis, Chiara Scognamiglio, Juri Brandolini, Giovanni Comacchio, Matteo Petroncini, Melania Guida, Filippo Terrando, Stefano Margaritora, Federico Rea, Marco Lucchi, Enrico Ruffini, POSTER PRESENTATION

(AB: 61). Robotic-Assisted Surgery for Large Thymomas: preliminary results on feasibility and safety in a single center experience; Beatrice Trabalza Marinucci, Fabiana Messa, Giorgia Piccioni, Matteo Tiracorrendo, Antonio D'Andrilli, Alessandra Siciliani, Erino Angelo Rendina, Mohsen Ibrahim, POSTER PRESENTATION

(AB: 63). Comparative Analysis of Surgical Approaches and Optimal Resection Extent in Thymoma Treatment; Yi Zhang, Gaojun Lu, Kejian Shi, Xin Zhao, Ku Zhang, Hao Cui, POSTER PRESENTATION

(AB: 65). Late Thymoma Occurrence After Thymectomy for Thymic Hyperplasia: Report of Two Cases; Carmine Caso, Martina Di Meo, Lucia Salatiello, Erica Pietroluongo, Angelo Luciano, Margaret Ottaviano, Giovannella Palmieri, Roberto Bianco, Alberto Servetto, POSTER PRESENTATION

(AB: 66). Are complement inhibitors safe for TAMG patients? A literary review and case report;  Angelo Luciano, Martina Di Meo, Erica Pietroluongo, Carmine Caso, Lucia Salatiello, Margaret Ottaviano, Roberto Bianco, Alberto Servetto, Giovannella Palmieri, POSTER PRESENTATION

(AB: 68). Robotic resection of thymoma recurrence with intra thoracic phrenic nerve reconstruction using a sural nerve graft; Jamie Romeo, Jos Maessen, Florit Marcuse, Monique Hochstenbag, Hester Gietema, Ulrich Lalji, Myrurgia Abdul Hamid, Patrique Segers, Shan Shan Qiu, POSTER PRESENTATION

(AB: 69). Mixed type A thymoma and micronodular thymoma with lymphoid stroma : a case report of an unusual tumor and litterature review; Rahma Ayadi, Rahma yaiche, Yasmine Dhouibi, Emna Braham, Olfa Ismail, Nadia Ben Jamaa, Aida Ayadi, POSTER PRESENTATION

(AB: 70). Thymoma in children, a rare mediastinal tumour : Pathological study of 6 cases and review of the literature; Rahma Ayadi, Rahma Yaiche, Emna Braham, Yasmine Dhouibi, Olfa Ismail, Nadia Ben jamaa, Aida Ayadi, POSTER PRESENTATION

(AB: 71). Continuing challenges of primary neuroendocrine neoplasms of the thymus : a clinicopathological characteristics of an uncommon tumor; Rahma Ayadi, Yasmine Barbirou, Rahma Yaiche, Emna Braham, Yasmine Dhouibi, Olfa Ismail, Nadia Ben jamaa, Aida Ayadi, POSTER PRESENTATION

(AB: 72). The Thymic Epithelial Tumors According to the New 2021 WHO Classification: TUNISIAN EXPERIENCE; Rahma Ayadi, Ichrak Hadhri, Rahma Yaiche, Emna Braham, Olfa Ismail, Nadia Ben jamaa, Aida Ayadi, POSTER PRESENTATION

(AB: 73). Immunopathological profile of patients with thymic epithelial tumour and Good syndrome in advanced stage.; Anna Maria Malfitano, Erica Pietroluongo, Michele Franceso Di Tolla, Fabiana Napolitano, Vittoria D’Esposito, Rocco Morra, Alberto Servetto, Roberto Bianco, Pietro Formisano, POSTER PRESENTATION

(AB: 74). Indications for postoperative radiation therapy for thymic tumors based on the new ninth TNM stage classification: a multicenter, retrospective study;  Gerrit Flier, Sonja Adebahr, Anca Grosu, Wolfgang Jungraithmayr, Bernward Passlick, Tanja Schimek-Jasch, POSTER PRESENTATION with brief discussion

(AB: 76). Survival Outcomes in Thymic Carcinoma: A Single-Center Experience; Erica Pietroluongo, Pietro De Placido, Martina Di Meo, Lucia Salatiello, Carmine Caso, Giovannella Palmieri, Roberto Bianco, Alberto Servetto, POSTER PRESENTATION

(AB: 78). FGFR1 amplification in thymic epithelial tumors (TET) : A study from 48 cases;  Véronique Hofman, Lara Chalabreysse, Jean-Philippe Dales, Romain Dubois, Audrey Mansuet-Lupo, Anne De Muret, Nicolas Piton, Isabelle Rouquette, Veronique Secq, Damien Sizaret, Vincent Thomas de Montpréville, Alice Millière, Salomé Lalvé, Pascale Missy, Clémentine Lemattre, Jonathan Benzaquen, Nicolas Girard, Paul Hofman, Benjamin Besse, Thierry Molina, ORAL PRESENTATION

(AB: 79). Assessment of apoptotic priming in thymic epithelial tumors to define hallmarks of pathogenesis and novel therapeutic strategies; Christopher Nabel, Xingping Qin, Cameron Fraser, Yolonda Colson, Michael Lanuti, Cameron Wright, Yin Hung, Kristopher Sarosiek, POSTER PRESENTATION  

(AB: 80). Surgical Outcomes and Prognostic Impact of Complete Resection in Thymic Epithelial Tumors: A 15-Year Experience from the National Cancer Institute of Mexico;  Lilia Cruz-Cantu, Jesus Martin-Perez, Azalea Olivares-Perez, Luis Antonio Miranda, Federico Magos, Miguel Angel Padilla, Federico Moreno-Avila, Oscar Arrieta, Francisco Lozano-Ruiz, POSTER PRESENTATION

(AB: 81). Two decades of robotic thymectomy: trends and insights from a retrospective study; Giovanni Comcchio, Alessandro Bonis, Giuseppe Cataldi, Giulia Pagliarini, Eleonora Faccioli, Marco Mammana, Giorgio Cannone, Alessandro Rebusso, Samuele Nicotra, Marco Schiavon, Andrea Dell'Amore, Federico Rea, POSTER PRESENTATION

(AB: 82). Surgical Management of TNM Stage IVA Thymoma and Thymic Carcinoma: the network TYME experience [4TYMEs].; Riccardo Orlandi, Paolo Mendogni, Mario Nosotti, Annalisa Trama, Monica Ganzinelli, Giovanni Leuzzi, Emanuele Voulaz, Paolo Zucali, Giovanni Comacchio, Giulia Pasello, Irene De Simone, Francesca Galli, Giovannella Palmieri, Erica Pietroluongo, Marcello Ambrogi, Vittorio Aprile, Lorenzo Rosso, ORAL PRESENTATION  
 
(AB: 83). Enrollment in Clinical Trials Among Italian Patients with Metastatic Thymic Epithelial Tumors: A Retrospective TYME Network; Analysis Nadia Cordua, Giuseppe Lo Russo, Martino Tommaso De Pas, Annalisa Trama, Matteo Perrino, Claudia Proto, Fabio Conforti, Marta Aliprandi, Monica Ganzinelli, Luigi Giovanni Cecchi, Giovanni Leuzzi, Chiara Catania, Alessandro Bertocchi, Giulia Montelatici, Laura Pala, Antonio Federico, Fabio De Vincenzo, Laura Giordano, Ilaria Piloni, Paolo Andrea Zucali, POSTER PRESENTATION

(AB: 84). A Predictive Model for Surgical Resectability in Thymic Epithelial Tumors Using Clinical Data: A Step Towards Integrating Radiomics and Histopathology;  Mohammed Ghazali, Mae Shu, DuyKhanh Ceppa, Rohan Maniar, POSTER PRESENTATION with brief discussion