ITMIG2024
Scientific and Educational Program
Wednesday, October 30th, 2024
08:00 - 08:15 WELCOME
ITMIG President: Anja Roden (Mayo Clinic, Rochester, MN, USA)
Program Committee Chair: Joshua Sonett (Columbia University/New York-Presbyterian Hospital, New York, USA)
Chair of Local Organizing Committee: Meinoshin Okumura (National Hospital Organization Osaka Toneyama Medical Center, Osaka, Japan)
08:15 - 10:05 SCIENTIFIC SESSION
Chairs:
Mirella Marino (Regina Elena National Cancer Institute, Rome, Italy)
Maria Isabel Leite (University of Oxford, Oxford, UK)
PART 1 - The Normal Thymus Development from Birth to Maturity: What We Know and Don’t Know
Pathology Alexander Marx (Institute of Pathology, University Medical Center Göttingen, Göttingen, Germany)
Radiology Jeanne Ackman (Massachusetts General Hospital, Boston, USA)
Immune System Development Avinash Bhandoola (National Cancer Institute, NIH, Bethesda, MD, USA)
PART 2 - When Things Go Awry - What Do We Understand so Far?
Immune Aberrations in Thymic Epithelial Tumors Arun Rajan (National Cancer Institute, NIH, Bethesda, MD, USA)
Neurology - Paraneoplastic Autoimmune Diseases Tatsusada Okuno (Osaka University, Osaka, Japan)
Q&A: Round Table (All Lecturers for Both Scientific Sessions)
10:05 - 10:15 BREAK
10:15 - 11:45 SCIENTIFIC SESSION
Focus on Thymic Carcinoma - What is Different from Thymoma
Chairs:
Yusuke Okuma (National Cancer Center Hospital, Tokyo, Japan)
Enrico Ruffini (University of Turin, Torino, Italy)
Thymic Carcinoma Imaging: Can We Predict? Chad Strange (University of Texas MD Anderson Cancer Center, Houston, TX, USA)
Pathology and Molecular Profiles
Yosuke Yamada (Kyoto University Hospital, Kyoto, Japan)
Medical Oncology: Present Options and Future Directions for Thymic Carcinoma Claudia Proto (Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy)
Radiation Oncology: Is Post-operative Radiotherapy Different?
Ritsuko Komaki (MD Anderson Cancer Center. Houston, Texas)
Surgery: Surgical Options for Known Thymic Carcinoma - Is It Different? Vincent Fang (Shanghai Chest Hospital, Shanghai, China)
Q&A: Thymic Carcinoma (All Lecturers)
11:45 - 12:35 LUNCH BREAK
(incl. 40 min) Lunch Seminar (Sponsored by Chugai) Heather Wakelee (Stanford University School of Medicine, Stanford Cancer Institute, Stanford, USA)
12:35 - 14:05 SCIENTIFIC SESSION
Novel Strategies in Thymic Tumors – What’s on the Horizon
Chairs:
Shun-Ichi Watanabe (National Cancer Center Hospital, Tokyo, Japan)
Dawn Owen (Mayo Clinic, Rochester, MN, USA)
Novel Strategies in Surgery:
New Techniques in Phrenic Nerve Reconstruction Sakashi Fujimori (Toranomon Hospital, Tokyo, Japan)
Robotic Extended Thymectomy with Subxiphoid Port
Jens Carsten Rückert (Charite, Humboldt University, Berlin, Germany)
Novel Strategies in Radiation Therapy:
High-dose Radiotherapy for Oligometastatic/Oligo-progressive Disease Andreas Rimner (University of Freiburg, Freiburg Germany)
Novel Strategies in Medical Oncology:
Developing Models of New Chemotherapy Asian Clinical Trials Network for Cancers Project: ATLAS Hitomi Okuma (National Cancer Center Hospital, Tokyo, Japan)
Targeted Therapy and Potential for Clinical Trials Chul Kim (Georgetown University, Washington, DC, USA)
Neoadjuvant and Adjuvant Approaches to Thymic Tumors
Magdalena Knetki-Wroblewska (Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland)
Q&A: Novel Strategies in Thymic Tumors (All Lecturers)
14:05 - 14:55 EDUCATIONAL SESSION
Myasthenia Gravis: Alfred Jaretzki Memorial Session
Chairs:
Mohammad Ashraghi (University of Oxford, Oxford, UK)
Marcin Zieliński (Pulmonary Hospital, Zakopane, Poland)
Basic Science Lecture: Thymic Hyperplasia in Myasthenia Gravis
Patricia Sikorski (Georgetown University, Washington, DC, USA)
DEBATE:
Biologic Therapies Will Replace the Role of Thymectomy in Myasthenia Gravis
Amanda Guidon (Massachusetts General Hospital, Boston, USA)
versus
Thymectomy in Non-Thymomatous Myasthenia Gravis is Proven Best Practice
Michael Lanuti (Massachusetts General Hospital, Boston, USA)
Q&A: Thymectomy and Myasthenia Gravis (All Lecturers)
14:55 - 15:05 BREAK
15:05 - 16:20 SCIENTIFIC SESSION
Other Mediastinal Tumors (SMARCA4-DUT/Thymic Carcinoids)
Chairs:
Anja Roden (Mayo Clinic, Rochester, MN, USA)
Heather Wakelee (Stanford University School of Medicine, Stanford Cancer Institute, Stanford, USA)
Imaging Features of Atypical Mediastinal Masses Tetsuro Araki (Massachusetts General Hospital, Boston, USA)
When Why and How to Biopsy Mediastinal Masses? Dirk Van Raemdonck (University Hospitals Leuven and KU Leuven University, Leuven, Belgium)
Pathology: This or that? How Do We Know? Andre Moreira (New York University, New York, NY, USA)
Oncology: How Do We Treat (SMARCA4-DUT/Thymic Carcinoids)? Margaret Ottaviano (Universita’ degli Studi di Napoli Federico II, Naples, Italy)
Q&A: Other Mediastinal Tumors (All Lecturers)
16:20 - 16:30 BREAK
16:30 - 17:30 SCIENTIFIC SESSION
Oral Abstract Session 1
Chairs:
Frank Detterbeck (Yale University, New Haven, USA)
Thierry Molina (Université Paris Cité , AP-HP, Paris, France)
Patterns of lymph node metastasis in patients with neuroendocrine thymic tumors: a retrospective study of 72 cases, PRESENTER: Wenqing Zhang, Shanghai Chest Hospital, Shanghai, China
Impact of size of primary tumor on survival in thymic epithelial tumor, PRESENTER: Asato Hashinokuchi, Kyushu University, Fukuoka, Japan
Surveillance trends after resection for thymic malignancy, PRESENTER: Giye Choe, Kaiser Permanente Oakland Medical Center, Oakland, California, USA
The impact of radical or limited resection of early-stage thymoma on long-term oncologic outcome and survival: a multi-institutional retrospective study, PRESENTER: Yi-Ting Yen, National Cheng Kung University, Tainan, Taiwan
Using Physician-Guided Artificial Intelligence to Assess Thymic Epithelial Tumors, PRESENTER: Nirmal Choradia, National Cancer Institute, Bethesda, MD, USA
Deep learning discriminates thymic epithelial tumors histological subtypes using Digital Pathology, PRESENTER: Matteo Sacco, University of Chicago, Chicago, IL, USA
17:30 -19:00 WELCOME RECEPTION