ITMIG2025
Scientific and Educational Program
DAY 1: Thursday, October 2, 2025
08:00 - 08:15 REGISTRATION AND WELCOME
08:15 - 09:00 TNM Staging Session
Chairs: Paul Van Schil (Antwerp, Belgium), Mirella Marino (Rome, Italy)
What we learned from the 9th edition of theTNM and what we expect to learn from the 10th edition, Enrico Ruffini (Torino, Italy)
Nodal dissection: What should surgeons do? Joshua Sonett (New York, USA)
The ITMIG-IASLC nodal map, Edith Marom (Tel Aviv, Israel)
Q&A, Discussion
09:00 - 10:00 Recent ITMIG Milestones
Chairs: Edith Marom (Tel Aviv, Israel), Andre Moreira (New York, USA)
ITMIG Standards and Definitions, Wentao Fang (Shanghai, China)
ITMIG Pathology Guidelines, Anja Roden (Rochester, USA
ITMIG Survey on Clinical and Pathology Practice of the Diagnosis and Treatment of Thymic Epithelial Tumors, Malgorzata Szolkowska (Warsaw Poland)
ITMIG Postoperative Radiation Therapy (PORT) project, Frank Detterbeck, New Haven, USA)
Q&A, Discussion
10:00 - 11:00 Oral Abstract Session 1
Chairs: Alexander Marx (Gottingen, Germany), Claudio Silva (Santiago, Chile)
Machine Learning Models from FDG PET/CT for Predicting Recurrence in Thymomas, Angelo Castello (Milan, Italy)
MIST: A Weakly Supervised Deep Learning System for Multicenter Diagnosis of Mediastinal Tumors, Xiaofeng Jiang (Chengdu, China)
Central pathology review of thymic tumors: updated analysis of diagnostic concordance in the French RYTHMIC cohort, Álvaro Gutiérrez (Villejuif, France)
Weakly Supervised AI-Based Subtyping of Thymic Epithelial Tumors Using H&E Whole Slide Images, Anna Salut Esteve Domínguez (Rotterdam, the Netherlands)
FGFR1 amplification in thymic epithelial tumors (TET): A study from 48 cases, Véronique Hofman (Nice, France)
Thymic Cancer in France: A Comprehensive Analysis of Incidence Based on French National Healthcare Data, Álvaro Gutiérrez (Villejuif, France)
11:00 - 11:30 Coffee Break
Poster presentations
11:30 - 12:15 ITMIG-TYME Joint Session
Chairs: Paolo Mendogni (Milan, Italy), Paolo Andrea Zucali (Milan, Italy)
Italian network TYME – Aims and Accomplishments, Giulia Galli (Pavia, Italy)
TETs Italian Registry – Aims and Accomplishments, Annalisa Trama (Milan, Italy)
ITMIG collaboration with national networks and future directions, Nicolas Girard (Paris, France)
Q&A, Discussion
12:15 - 13:00 Bilateral Robotic Thymectomy in Rheumatoid Arthritis: A Multidisciplinary Approach to Complex Surgery.
Case Presentation with Audience Participation
Chairs: Roger Hsu (Toronto, Canada), Alberto De La Vega (San Paolo, Brazil)
Presentation with clinical, radiological and pathological comments
CASE PRESENTATION: Davide Tosi (Milan, Italy)
Radiology: Maria Carmela Andrisani (Milan, Italy)
Pathology: Giorgio Croci (Milan, Italy)
Pulmonology: Antonella Arcadu (Milan, Italy)
Q/A, Discussion
13:00 - 13:45 LUNCH BREAK
SESSION WITH REPRESENTATIVES OF PATIENTS
13:45 - 14:45 Management of Recurrent and Re-recurrent Disease
Chairs: Yusuke Okuma (Tokyo, Japan), Rohan Maniar (Indiana, USA)
CASE PRESENTATION: Giuseppe Calabrese (Rome, Italy)
Recurrence and primary TETs: Is it the same disease? Marco Chiappetta (Catanzaro, Italy)
Innovative therapies in recurrences of thymic tumors, Christopher Nabel (Boston, USA)
Round table/audience discussion
The ITMIG recurrence classification: validation and possible updates, Filippo Lococo (Rome, Italy)
14:45 - 15:45 Anti-angiogenesis, Immunotherapy and Novel Therapies in Thymic Carcinoma
Chairs: Giovanella Palmieri (Naples, Italy), Nicolas Girard (Paris, France)
The immunotherapy landscape: from clinical trials to clinical practice, Margaret Ottaviano (Naples, Italy
Anti-angiogenics and combinations, Sukhmani K. Padda, Fox (Philadelphia, USA
New treatment strategies: Antibody Drug Conjugates and bispecific Antibody Drug Conjugates, Chul Kim (Washington, USA)
Platinum based chemotherapy: still the best option? Martina Imbimbo (Bellinzona, Switzerland)
Q&A, Discussion
15:45 - 16:15 Coffee break
Poster presentations
16:15 - 17:15 Neoadjuvant therapies: When, how and why
Chairs: Patrick Loehrer (Indiana, USA); Usman Ahmad (Abu Dhabi, UAE)
What do surgeons need to know from imaging in advanced thymic epithelial tumors? Katarzyna Blasinska (Warsaw, Poland)
Potential neoadjuvant use of immunotherapy and targeted therapy in 2025, Magdalena Knetki-Wróblewska, (Warsaw, Poland)
Surgical challenges after neoadjuvant therapy, Andrea Billè (London, UK)
How to assess pathologic response after neoadjuvant therapy, Andre Moreira, (New York, USA)
Q&A, Discussion
17:15 - 18:15 Nuclear Medicine and Interventional Radiology in TETs - a tailored approach
Chairs: Jeanne Ackman (Boston, USA), Claudio Silva (Santiago, Chile)
Prognostic value and role of FDG-PET-CT: Initial staging and after therapy, Luca Urso (Ferrara, Italy)
Beyond FDG, Angelo Castello (Milan, Italy)
Percutaneous ablation therapy in isolated or multiple extra-mediastinal thymic epithelial lesions: is it worthwhile? Giampaolo Carrafiello (Milan, Italy)
How to manage difficult cases? An intrapleural recurrence case, Dirk Van Raemdonck, (Leuven, Belgium)
Q&A, Discussion
19:00 - 20:00 WELCOME RECEPTION